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Limited Competition: Microphysiological Systems Database Center (MPS DC) (U24 Clinical Trials Not Allowed)

NIH Funding Opportunities (Notices, PA, RFA) - January 17, 2020 - 10:16am
Funding Opportunity RFA-TR-20-002 from the NIH Guide for Grants and Contracts. This Limited Competition Funding Opportunity Announcement (FOA) invites an application from the currently funded Microphysiological Systems (MPS) Database Center (MPS DC) which supports the NIH Tissue Chip Consortium. The overall goal of the MPS DC is to integrate the efforts of all funded components of the Tissue Chip Consortium and serve as a community-wide resource for deposition of tissue chip data, standards, protocols, and analytical tools. The MPS DC is expected to continue to be the central clearinghouse for tissue chips data management, and to incorporate novel approaches and technologies for data management, data mining and meta-analyses, and data sharing across many organs and tissues, diseases, data types, and tissue chip platforms. The MPS DC is expected to provide different levels of public and tiered access to tissue chip information for basic and clinical researchers, academic and practicing physicians, the pharmaceutical industry, NIH, FDA and other government agencies, patients, and the lay public. The MPS DC will work with IQ Consortium members to develop and make available a secure, customizable coordinated data management system for collection, storage, and analyses of diverse data types from multiple tissue chip platforms being developed and used for drug screening, safety and efficacy testing. The application must include a clear and well laid out plan to be completely independent and self-sustaining before the end of the requested NIH support.
Categories: NIH

Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed)

NIH Funding Opportunities (Notices, PA, RFA) - January 17, 2020 - 2:05am
Funding Opportunity PAR-20-097 from the NIH Guide for Grants and Contracts. This funding opportunity announcement is designed to support biomedical knowledgebases. Biomedical knowledgebases under this announcement should have the primary function to extract, accumulate, organize, annotate, and link growing bodies of information related to core datasets. Support for data curation should include efficient and effective methods of curation that scale to the needs of community and include semi-automated methods. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of operation of the knowledgebase. Applications that have a significant focus on software and tool development are not appropriate for this activity.
Categories: NIH

Biomedical Data Repository (U24 - Clinical Trials Not Allowed)

NIH Funding Opportunities (Notices, PA, RFA) - January 17, 2020 - 2:05am
Funding Opportunity PAR-20-089 from the NIH Guide for Grants and Contracts. This funding opportunity announcement is designed to support biomedical data repositories. Biomedical data repositories under this announcement should have the primary function to ingest, archive, preserve, manage, distribute, and make accessible the data related to a particular system or systems. Support for data curation must be limited to that which improves the efficiency and accessibility of data ingestion, management, and use and reuse by the user communities. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of operation of the repository. Applications that have a significant focus on software and tool development are not appropriate for this activity.
Categories: NIH

Patients with newly diagnosed musculoskeletal pain are prescribed opioids more often than recommended

NIH News Releases - January 16, 2020 - 6:00pm
NIH study shows treatment recommendations impacted by patient and physician factors.

Categories: NIH

KUH Predoctoral to Postdoctoral Fellow Transition Award (F99/K00)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 1:27pm
Funding Opportunity RFA-DK-19-032 from the NIH Guide for Grants and Contracts. The purpose of the Kidney, Urology or Hematology (KUH) Predoctoral to Postdoctoral Fellow Transition Awards (F99/K00) is to recruit exceptional graduate students from diverse research fields to pursue postdoctoral training focused on Kidney, Urology or Hematology (K, U, or H) research. Talented graduate students from disciplines including, but not limited to, engineering, statistics, data science, imaging, biochemistry and genetics are invited to apply to this opportunity. Graduate students who are already involved in K, U, or H research are not eligible for the F99/K00 award and are instead encouraged to apply for the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31, PA-19-195). Prospective applicants are strongly encouraged to contact the NIDDK Program Official prior to initiating plans for application submission. This Funding Opportunity Announcement (FOA) does not allow applicants to propose to lead an independent clinical trial, but does allow applicants to propose research experience in a clinical trial led by a sponsor or co-sponsor.
Categories: NIH

Accelerating Medicine Partnership in Parkinsons disease (AMP PD) data use and analysis (U01 Clinical trials not allowed)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 1:03pm
Funding Opportunity RFA-NS-20-027 from the NIH Guide for Grants and Contracts. The FOA invites applications that will apply computational approaches to the integration and analysis of clinical, genomic and transcriptomic data from the Accelerating Medicine Partnership in Parkinsons disease (AMP PD) to advance the identification of algorithms, biomarkers, and disease pathways related to the diagnosis, prognosis and progression of Parkinsons disease. Development of tools and workflows for data visualization and integration across data modalities and their application to AMP PD data are also supported.
Categories: NIH

Research Answers to National Cancer Institute's (NCI) Provocative Questions (R01 Clinical Trial Optional)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 12:25pm
Funding Opportunity RFA-CA-20-004 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support research projects designed to solve specific problems and paradoxes in cancer research identified by the National Cancer Institute (NCI) Provocative Questions Initiative. These problems and paradoxes phrased as questions are not intended to represent the full range of NCI's priorities in cancer research. Rather, they are meant to challenge researchers to think about and elucidate specific problems in key areas of cancer research that are deemed important and have not received sufficient attention. Some of these "Provocative Questions" (PQs) stem from intriguing but older, neglected observations that have never been adequately explored. Other PQs are built on more recent findings that are perplexing or paradoxical, revealing important gaps in current knowledge. Finally, some PQs reflect problems that traditionally have been thought to be intractable but that now may be open to investigations using new strategies and recent technical advances. The current issuance of the PQ Initiative includes an updated set of 12 PQs. Each research project proposed in response to this FOA must be focused on addressing the research problems defined by a specific PQ selected from the list. Projects proposed to address PQs may use strategies that incorporate ideas and approaches from multiple disciplines, as appropriate. Transdisciplinary projects are encouraged if they serve the scientific focus of the selected PQ.
Categories: NIH

NIMH Research Education Programs for Psychiatry Residents (R25- Independent Clinical Trial Not Allowed)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 5:27am
Funding Opportunity PAR-20-094 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences.
Categories: NIH

NIMH Mentoring Networks for Mental Health Research Education (R25 Clinical Trial Not Allowed)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 5:16am
Funding Opportunity PAR-20-080 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs.
Categories: NIH

Research Answers to National Cancer Institute's (NCI) Provocative Questions (R21 Clinical Trial Optional)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 5:00am
Funding Opportunity RFA-CA-20-005 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support research projects designed to solve specific problems and paradoxes in cancer research identified by the National Cancer Institute (NCI) Provocative Questions Initiative. These problems and paradoxes phrased as questions are not intended to represent the full range of NCI's priorities in cancer research. Rather, they are meant to challenge researchers to think about and elucidate specific problems in key areas of cancer research that are deemed important and have not received sufficient attention. Some of these "Provocative Questions" (PQs) stem from intriguing but older, neglected observations that have never been adequately explored. Other PQs are built on more recent findings that are perplexing or paradoxical, revealing important gaps in current knowledge. Finally, some PQs reflect problems that traditionally have been thought to be intractable but that now may be open to investigations using new strategies and recent technical advances. The current issuance of the PQ Initiative includes an updated set of 12 PQs. Each research project proposed in response to this FOA must be focused on addressing the research problems defined by a specific PQ selected from the list. Projects proposed to address PQs may use strategies that incorporate ideas and approaches from multiple disciplines, as appropriate. Transdisciplinary projects are encouraged if they serve the scientific focus of the selected PQ
Categories: NIH

Combating Antibiotic-Resistant Bacteria (CARB) Interdisciplinary Research Units (U19 Clinical Trial Not Allowed)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 4:45am
Funding Opportunity RFA-AI-20-001 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits applications to establish Combating Antibiotic-Resistant Bacteria (CARB) Interdisciplinary Research Units (CARBIRUs) focused on improving our understanding of bacterial and host factors important for antibacterial resistance and infection to inform development of new approaches to prevent, diagnose, and treat antibacterial-resistant infections.
Categories: NIH

Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 4:27am
Funding Opportunity PAR-20-093 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. The NIMH seeks teams of researchers working at different levels of analysis and employing integrative, novel, and creative experimental approaches to address high-risk, high-impact questions with the primary objectives of: (a) advancing the state of the science in basic brain and behavior research that will uncover and dissect the underlying mechanisms that will ultimately provide the foundation for understanding mental disorders; (b) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses; and/or (c) advancing our understanding of the neurobehavioral developmental mechanisms and trajectories of psychopathology that begin in childhood and adolescence. The Conte Centers program is intended to support interdisciplinary basic neuroscience or translational research that demonstrates an extraordinary level of synergy, integration, and potential for advancing the state of the field. This program is intended only for projects that could not be achieved using other, more standard grant mechanisms.
Categories: NIH

Centers for Collaborative Research in Fragile X and FMR1-Associated Conditions (P50 Clinical Trial Optional)

NIH Funding Opportunities (Notices, PA, RFA) - January 16, 2020 - 3:50am
Funding Opportunity RFA-HD-20-003 from the NIH Guide for Grants and Contracts. This FOA invites applications for Centers for Collaborative Research in Fragile X and FMR1-Associated Conditions (hereafter termed "Fragile X Centers"). Successful Centers will be composed of multidisciplinary teams of investigators collaborating to address specific research priorities identified in the Strategic Plan.
Categories: NIH
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