NIH

Gene therapy restores immune function in children with rare immunodeficiency

NIH News Releases - May 11, 2021 - 1:00pm
Researchers found that 48 of 50 children retained their replenished immune system function two to three years later and did not require additional treatments for ADA-SCID.

Categories: NIH

SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)

Funding Opportunity RFA-ES-21-005 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to further the development of Advanced Technology Training (ATT) products for: the health and safety training of hazardous materials (HAZMAT) workers; waste treatment personnel; skilled support personnel associated with an emergency/disaster; emergency responders in biosafety response, infectious disease training and cleanup; emergency responders in disasters and resiliency training; and for ATT tools to assist in responding to environmental disasters. ATT as defined by the Worker Training Program (WTP) includes, but is not limited to, online training, mobile device training, virtual reality, and serious gaming, which complement all aspects of training from development to evaluation including advanced technologies that enhance, supplement, improve, and provide health and safety training for hazardous materials workers. These products must complement the goals and objectives of WTP. The major objective of the NIEHS WTP is to prevent work related harm by assisting in the training of workers in how best to protect themselves and their communities from exposure to hazardous materials. The financial support for this initiative comes directly from NIEHS Worker Education and Training Branch SBIR funds.
Categories: NIH

Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 - Clinical Trial Optional)

Funding Opportunity PA-21-180 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental disorder conditions. Relevant approaches may include both those that are novel, and those that are commonly used in practice but lack an evidence base. This FOA provides resources for assessing the feasibility, acceptability, and utility of these approaches, in addition to usual trial preparation activities.
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T32 Training Program for Institutions That Promote Diversity (T32 Clinical Trial Not Allowed)

Funding Opportunity RFA-HL-22-001 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to enhance the participation of individuals from nationally underrepresented backgrounds in cardiovascular, pulmonary, hematologic and sleep disorders research across the career development continuum by providing support to institutions that promote diversity. The NHLBI's T32 Training Program for Institutions That Promote Diversity is a Ruth L. Kirschstein National Research Service Award Program intended to support training of predoctoral and health professional students and individuals in postdoctoral training institutions with an institutional mission focused on serving health disparity populations not well represented in scientific research, or institutions that have been identified by federal legislation as having an institutional mission focused on these populations, with the potential to develop meritorious training programs in cardiovascular, pulmonary, and hematologic diseases, and sleep disorders. These institutions are uniquely positioned to engage minority and other health disparity populations in research, translation, and implementation of research advances that impact health outcomes, as well as provide health care for these populations. This FOA does not allow appointed trainees to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.
Categories: NIH

Emerging Science and Technology in Transplantation (U01 Clinical Trial Not Allowed)

Funding Opportunity RFA-AI-21-016 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications from institutions or organizations to participate in a cooperative research group focused on transplantation immunology research in three priority areas: 1) microbiota; 2) intravital imaging; and 3) targeted therapeutic delivery. The purpose of this FOA is to stimulate the formation of interdisciplinary collaborations and facilitate the application of new scientific developments and technologies to the field of transplant immunology. Applying these advances to transplantation science will provide novel insights into the nature of alloimmune responses and reveal new avenues to diagnose, treat and prevent allograft rejection or promote immunologic tolerance.
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<a href="/news-events/nih-research-matters/app-may-help-identify-children-autism-spectrum-disorder">App may help identify children with autism spectrum disorder</a>

NIH Research Matters - May 11, 2021 - 12:00am
Researchers developed a prototype app that screens toddlers for autism spectrum disorder by tracking eye movements during videos on a tablet or smartphone.
Categories: NIH

<a href="/news-events/nih-research-matters/supplement-improves-glucose-metabolism-womens-muscle">Supplement improves glucose metabolism in women’s muscle</a>

NIH Research Matters - May 11, 2021 - 12:00am
The muscles of women who took a supplement called nicotinamide mononucleotide for 10 weeks had improvements in the ability to process sugar.
Categories: NIH

<a href="/news-events/nih-research-matters/biosensor-advances-drug-discovery">Biosensor advances drug discovery</a>

NIH Research Matters - May 11, 2021 - 12:00am
Researchers developed a sensor that helped them identify a psychedelic-related drug with antidepressant-like effects that wasn’t hallucinogenic.
Categories: NIH

Long-lasting medications may improve treatment satisfaction in people with opioid use disorder

NIH News Releases - May 10, 2021 - 3:00pm
NIH leaders emphasize the importance of patient voices in addiction medication development.

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